Investigating how sex affects mental health and cognitive outcomes in adults with congenital heart disease

Sex Differences in Psychosocial and Neurocognitive Outcomes in Adults with Moderate to Complex Congenital Heart Disease

NIH-funded research University of California Los Angeles · NIH-10991692

This study is looking at how congenital heart disease affects the mental health and thinking skills of young adults, both men and women, to better understand their unique challenges and improve support for them.

Quick facts

Grant typeFellowship grant
Study typeNIH-funded research
Funding institutionUniversity of California Los Angeles NIH-funded
Lab location1 site (Los Angeles, United States)
Project IDNIH-10991692 on NIH RePORTER

What this research studies

This research focuses on understanding the differences in psychosocial and neurocognitive outcomes between male and female adults who have moderate to complex congenital heart disease (CHD). It aims to recruit 180 participants aged 18 to 40 with CHD, along with 40 healthy controls, to assess various cognitive functions and mental health issues such as anxiety and depression. By examining these differences, the study seeks to identify specific needs and challenges faced by these individuals, which can inform better care and support strategies. The research will utilize a cross-sectional approach to gather data on cognitive performance and psychosocial well-being.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 18 to 40 who have been diagnosed with moderate to complex congenital heart disease.

Not a fit: Patients who do not have congenital heart disease or are outside the age range of 18 to 40 may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved mental health support and tailored interventions for adults with congenital heart disease based on their sex.

How similar studies have performed: While some studies have explored neurocognitive and psychosocial outcomes in adults with congenital heart disease, this research is novel in its focus on sex differences in these areas.

Where this research is happening

Los Angeles, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.