Investigating how Serum Amyloid A contributes to stroke damage
Role of Serum Amyloid A in the Pathogenesis of Stroke
This study is looking at how a protein called Serum Amyloid A (SAA) affects inflammation and brain injury after a stroke, with the goal of finding new ways to predict recovery and improve care for stroke patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | James a. Haley VA Medical Center NIH-funded |
| Lab location | 1 site (Tampa, United States) |
| Project ID | NIH-11061807 on NIH RePORTER |
What this research studies
This research focuses on understanding the role of Serum Amyloid A (SAA) proteins in the inflammation process related to stroke. It examines how SAA levels rise significantly during acute inflammation and their impact on brain injury following a stroke. By studying the mechanisms of SAA, the research aims to identify new biomarkers that could predict stroke outcomes and develop potential interventions to improve patient care. The approach includes analyzing SAA levels in both animal models and human subjects to establish a clearer link between SAA and stroke progression.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who have experienced a stroke or are at high risk for stroke.
Not a fit: Patients who have not experienced a stroke or do not have risk factors for stroke may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new ways to predict stroke outcomes and improve treatment strategies for patients.
How similar studies have performed: Previous studies have shown promising results regarding the role of SAA in stroke progression, indicating that this research builds on established findings.
Where this research is happening
Tampa, United States
- James a. Haley VA Medical Center — Tampa, United States (Active)
Researchers
- Principal investigator: Kindy, Mark S. — James a. Haley VA Medical Center
- Study coordinator: Kindy, Mark S.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.