Investigating how serine metabolism affects oral cancer development
Official title: The role of serine metabolism on the evolution of oral squamous cell carcinoma
Funded at Boston University Medical Campus · NIH-10929416 · Data updated 2026-11-12
This study is looking at how changes in a substance called serine might affect the behavior of oral squamous cell carcinoma, a tough-to-treat type of cancer, to help find better ways to manage and treat it for patients like you.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston University Medical Campus NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | September 12, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $49,774 |
| NIH project number | 5F31DE032892-02 |
| Project ID | NIH-10929416 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with oral squamous cell carcinoma, particularly those with advanced or treatment-resistant disease.
✕Less likely to help
Patients with other types of cancers or those without oral squamous cell carcinoma may not receive direct benefits from this research.
What this research studies
This research explores the role of serine metabolism in oral squamous cell carcinoma (OSCC), a type of cancer that is difficult to treat and often leads to poor outcomes. The study examines how changes in serine levels can influence cancer cell behavior, particularly in terms of growth and differentiation. By analyzing the effects of serine starvation on cancer cells, researchers aim to understand the underlying mechanisms that contribute to the aggressiveness of OSCC and identify potential new therapeutic targets. Patients may benefit from insights gained into how to better treat or manage this challenging cancer.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatment options for patients with oral squamous cell carcinoma.
How similar studies have gone: Previous research has shown promising results in targeting metabolic pathways in cancer treatment, suggesting that this approach may yield beneficial outcomes.
Where this research is happening
-
Boston University Medical Campus
Boston, United States Active
Researchers
- Principal investigator: Jankowski, Stacy — Boston University Medical Campus
- Study coordinator: Jankowski, Stacy
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.