Investigating how sensitization to a common fungus affects asthma development
The role of Alternaria fungal sensitization in asthma pathogenesis
This study is looking at how the Alternaria fungus affects people with asthma, trying to find out why some people are more sensitive to it than others, which could help us understand asthma triggers better and find new ways to treat it.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | La Jolla Institute for Immunology NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-11222453 on NIH RePORTER |
What this research studies
This research explores the role of the Alternaria fungus in asthma, particularly why some individuals become sensitized to it while others do not. The study will examine the immune mechanisms and specific cell types involved in this sensitization process. By analyzing the differences in immune responses between healthy individuals and those with asthma, the researchers aim to uncover protective factors and pathogenic features associated with Alternaria sensitization. This could lead to a better understanding of asthma triggers and potential new treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research include adults who have asthma or are sensitized to Alternaria fungus.
Not a fit: Patients who do not have asthma or any form of sensitization to Alternaria may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for asthma related to fungal allergens.
How similar studies have performed: Previous research has shown promising results in understanding the immune responses to allergens, suggesting that this approach may yield valuable insights.
Where this research is happening
La Jolla, United States
- La Jolla Institute for Immunology — La Jolla, United States (Active)
Researchers
- Principal investigator: Vijayanand, Pandurangan — La Jolla Institute for Immunology
- Study coordinator: Vijayanand, Pandurangan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.