Investigating how SARS-CoV-2 affects organs and responses to therapy using specialized imaging.
ACE2-targeted PET radiotracers for investigating spatiotemporal distribution of SARS-CoV-2 organ injury and therapy response.
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · NIH-10681427
This study is looking at how the COVID-19 virus affects different organs in the body and how we can create better treatments, using a special imaging technique to see where the virus is and how the body responds, which could help patients understand their condition and improve their care.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO (nih funded) |
| Locations | 1 site (SAN FRANCISCO, UNITED STATES) |
| Trial ID | NIH-10681427 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding the impact of the SARS-CoV-2 virus on various organs in the body and how effective therapies can be developed. It utilizes a new imaging technique called ACE2-targeted PET radiotracing to visualize the distribution of the virus and the body's response to treatments. By studying the receptor ACE2, which is crucial for the virus's entry into cells, the research aims to improve therapeutic strategies for COVID-19 and potentially other diseases linked to ACE2. Patients may benefit from insights gained about the timing and location of organ injury caused by the virus, which can inform treatment decisions.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with COVID-19 who are experiencing organ-related complications.
Not a fit: Patients who have not contracted COVID-19 or those with unrelated health conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for COVID-19 and related conditions, improving patient outcomes.
How similar studies have performed: Previous research has shown promise in using imaging techniques to study viral infections, suggesting that this approach could yield valuable insights.
Where this research is happening
SAN FRANCISCO, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN FRANCISCO — SAN FRANCISCO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WILSON, DAVID M — UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
- Study coordinator: WILSON, DAVID M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.