Investigating how RSV immunoprophylaxis affects respiratory health in children with Down syndrome
The effectiveness of RSV immunoprophylaxis on the short- and long- term respiratory morbidity in children with Down syndrome
This study is looking at how well a preventive treatment for RSV can help children with Down syndrome stay healthy and avoid breathing problems, while also checking if it's a good value for families over time.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project ID | NIH-10768550 on NIH RePORTER |
What this research studies
This research focuses on children with Down syndrome, who are at a higher risk for respiratory syncytial virus (RSV) infections. The study aims to evaluate the effectiveness of RSV immunoprophylaxis in reducing both immediate and long-term respiratory issues caused by RSV infections. By administering this preventive treatment, the researchers hope to gather data on its impact on respiratory health and overall well-being in these children. The study will also assess the cost-effectiveness of this intervention over time.
Who could benefit from this research
Good fit: Ideal candidates for this research are children with Down syndrome, particularly those who are at risk for RSV infections.
Not a fit: Patients without Down syndrome or those who do not have a risk of RSV infections may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved respiratory health and reduced hospitalizations for children with Down syndrome.
How similar studies have performed: Previous research has indicated that RSV immunoprophylaxis can be effective in reducing RSV-related morbidity in high-risk populations, suggesting potential success for this approach in children with Down syndrome.
Where this research is happening
Nashville, United States
- Vanderbilt University Medical Center — Nashville, United States (Active)
Researchers
- Principal investigator: Wu, Pingsheng — Vanderbilt University Medical Center
- Study coordinator: Wu, Pingsheng
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.