Investigating how RNA regulation affects allergic airway inflammation in asthma
Official title: RNA regulatory circuits in allergic airway inflammation
Funded at University of California, San Francisco · NIH-11067490 · Data updated 2026-11-12
This study is looking at how certain RNA molecules affect inflammation in asthma, especially the allergic type, to find new ways to help manage asthma symptoms and prevent flare-ups, which could lead to better treatments for patients.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project start | May 1, 2025 |
| Funding year | 2025 |
| Award (this year) | $81,364 |
| NIH project number | 1F32AI188624-01 |
| Project ID | NIH-11067490 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with asthma, particularly those experiencing allergic-type symptoms.
✕Less likely to help
Patients with non-allergic asthma or those whose asthma is not driven by type 2 inflammation may not benefit from this research.
What this research studies
This research focuses on understanding the role of RNA regulatory circuits in the inflammation associated with asthma, particularly the type 2 allergic response. It aims to identify how RNA binding proteins interact with specific regions of mRNA to influence the stability and activity of inflammatory signals in airway cells. By exploring these mechanisms, the research seeks to uncover potential targets for new treatments that could help manage asthma symptoms and reduce exacerbations. Patients may benefit from insights that could lead to more effective therapies for asthma management.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies that better control asthma inflammation and improve patient outcomes.
How similar studies have gone: Previous research has shown promise in targeting RNA regulatory mechanisms in other inflammatory conditions, suggesting potential for success in this area as well.
Where this research is happening
-
University of California, San Francisco
San Francisco, United States Active
Researchers
- Principal investigator: Garudadri, Suresh — University of California, San Francisco
- Study coordinator: Garudadri, Suresh
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.