Investigating how rhinovirus-C infections affect asthma in children
Models of rhinovirus-C respiratory infection and asthma
This study is looking at how a certain virus called RV-C can cause bad respiratory infections and worsen asthma in young kids, with the goal of finding better ways to help those who are affected.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-10899542 on NIH RePORTER |
What this research studies
This research focuses on understanding the role of a specific type of rhinovirus, known as RV-C, in causing severe respiratory infections and asthma exacerbations in young children. By using animal models, the researchers will examine how RV-C infections lead to inflammation and other changes in the airways that may contribute to asthma development. The study aims to identify the mechanisms behind these infections and their impact on the immune response in the lungs, which could help in developing better treatments for affected children.
Who could benefit from this research
Good fit: Ideal candidates for this research are children under the age of 11, particularly those with a history of respiratory infections or asthma.
Not a fit: Patients who are older than 11 years or do not have a history of respiratory issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for asthma triggered by rhinovirus-C infections in children.
How similar studies have performed: Previous research has shown that understanding viral infections can lead to significant advancements in asthma treatment, indicating a promising avenue for this investigation.
Where this research is happening
Ann Arbor, United States
- University of Michigan at Ann Arbor — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Hershenson, Marc B. — University of Michigan at Ann Arbor
- Study coordinator: Hershenson, Marc B.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.