Investigating how respiratory viruses affect lung health in transplant patients
Longitudinal Impact of Respiratory Viruses on Bronchiolitis Obliterans Syndrome in Allogeneic Hematopoietic Cell Transplant Recipients
This study is looking at how respiratory viruses affect lung health in people who have had a stem cell transplant and are dealing with bronchiolitis obliterans syndrome, and it will use home devices to keep track of their lung function over time to help catch any problems early.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Fred Hutchinson Cancer Center NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-10995284 on NIH RePORTER |
What this research studies
This research focuses on understanding the impact of respiratory viruses on bronchiolitis obliterans syndrome (BOS) in patients who have undergone allogeneic hematopoietic cell transplantation. It aims to identify how these viruses contribute to lung dysfunction and poor health outcomes over time. By using mobile wireless home spirometry, the study will monitor lung function in patients, allowing for early diagnosis and better tracking of disease progression. The research will involve multiple centers and will follow patients longitudinally to gather comprehensive data on their respiratory health.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have received an allogeneic hematopoietic cell transplant and are at risk for bronchiolitis obliterans syndrome.
Not a fit: Patients who have not undergone allogeneic hematopoietic cell transplantation or do not have respiratory complications may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved management and treatment strategies for lung complications in transplant patients.
How similar studies have performed: Previous research has indicated that monitoring respiratory viruses can provide valuable insights into lung health, suggesting that this approach may yield significant findings.
Where this research is happening
Seattle, United States
- Fred Hutchinson Cancer Center — Seattle, United States (Active)
Researchers
- Principal investigator: Cheng, Guang-Shing — Fred Hutchinson Cancer Center
- Study coordinator: Cheng, Guang-Shing
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.