Investigating how reproductive aging affects racial differences in Alzheimer's disease risk.
Official title: The Role of Reproductive Aging for Racial Differences in AD/ADRD from Midlife to Older Age
Funded at Stanford University · NIH-10983684 · Data updated 2026-11-12
This study is looking at how changes in women's reproductive health, like menopause, might affect the risk of developing Alzheimer's and related dementias, especially for Black women who may go through menopause earlier, to help find ways to reduce that risk.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project start | August 15, 2024 |
| Project end | July 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $131,004 |
| NIH project number | 1K99AG084897-01A1 |
| Project ID | NIH-10983684 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include women aged 40 and older, particularly those who are Black or have undergone reproductive surgeries.
✕Less likely to help
Patients who are younger than 40 or do not identify as women may not receive benefit from this research.
What this research studies
This research explores the connection between reproductive aging and the risk of Alzheimer's Disease and related dementias (AD/ADRD), particularly focusing on racial disparities. It examines how factors like menopause and reproductive surgeries may influence the risk of developing AD/ADRD, especially among Black women who may experience earlier menopause. The study aims to gather comprehensive data to understand these relationships better and identify potential modifiable risk factors. By analyzing these factors, the research seeks to provide insights that could lead to improved prevention strategies for at-risk populations.
Why it matters
Potential benefit: If successful, this research could lead to targeted interventions that reduce the risk of Alzheimer's disease in women, particularly among Black individuals.
How similar studies have gone: While some studies have explored menopause and Alzheimer's risk, this research aims to address specific racial disparities, making it a novel approach.
Where this research is happening
-
Stanford University
Stanford, United States Active
Researchers
- Principal investigator: Reeves, Alexis — Stanford University
- Study coordinator: Reeves, Alexis
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.