Investigating how reproductive aging affects racial differences in Alzheimer's disease risk.
The Role of Reproductive Aging for Racial Differences in AD/ADRD from Midlife to Older Age
['FUNDING_CAREER'] · STANFORD UNIVERSITY · NIH-10983684
This study is looking at how changes in women's reproductive health, like menopause, might affect the risk of developing Alzheimer's and related dementias, especially for Black women who may go through menopause earlier, to help find ways to reduce that risk.
Quick facts
| Phase | ['FUNDING_CAREER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | STANFORD UNIVERSITY (nih funded) |
| Locations | 1 site (STANFORD, UNITED STATES) |
| Trial ID | NIH-10983684 on ClinicalTrials.gov |
What this research studies
This research explores the connection between reproductive aging and the risk of Alzheimer's Disease and related dementias (AD/ADRD), particularly focusing on racial disparities. It examines how factors like menopause and reproductive surgeries may influence the risk of developing AD/ADRD, especially among Black women who may experience earlier menopause. The study aims to gather comprehensive data to understand these relationships better and identify potential modifiable risk factors. By analyzing these factors, the research seeks to provide insights that could lead to improved prevention strategies for at-risk populations.
Who could benefit from this research
Good fit: Ideal candidates for this research include women aged 40 and older, particularly those who are Black or have undergone reproductive surgeries.
Not a fit: Patients who are younger than 40 or do not identify as women may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to targeted interventions that reduce the risk of Alzheimer's disease in women, particularly among Black individuals.
How similar studies have performed: While some studies have explored menopause and Alzheimer's risk, this research aims to address specific racial disparities, making it a novel approach.
Where this research is happening
STANFORD, UNITED STATES
- STANFORD UNIVERSITY — STANFORD, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: REEVES, ALEXIS — STANFORD UNIVERSITY
- Study coordinator: REEVES, ALEXIS
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.