Investigating how repeated CBD use affects cannabis addiction and pain relief
Official title: Effects of Repeated CBD Administration on Cannabis Abuse-Liability and Analgesia: A Human Laboratory Study
Funded at Columbia University Health Sciences · NIH-10663671 · Data updated 2026-11-12
This study is looking at how different amounts of CBD can affect the experience of smoking cannabis and help with pain relief for healthy adults who already use cannabis.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia University Health Sciences NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | August 1, 2024 |
| Project end | July 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $180,360 |
| NIH project number | 1K01DA056692-01A1 |
| Project ID | NIH-10663671 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are healthy adults aged 21 and older who are regular cannabis smokers.
✕Less likely to help
Patients who do not use cannabis or have chronic pain conditions may not benefit from this research.
What this research studies
This research explores the effects of cannabidiol (CBD) on cannabis use and pain relief in healthy adult cannabis smokers. Participants will receive varying doses of CBD over 15 days while smoking cannabis in a controlled laboratory setting. The study aims to measure the impact of CBD on the subjective effects of cannabis and its potential to enhance pain relief. By understanding these interactions, the research seeks to provide insights into the therapeutic use of cannabis and CBD for managing pain.
Why it matters
Potential benefit: If successful, this research could lead to improved pain management strategies for individuals using cannabis and CBD.
How similar studies have gone: Previous research has shown promising results regarding the analgesic effects of CBD, but this specific approach is relatively novel.
Where this research is happening
-
Columbia University Health Sciences
New York, United States Active
Researchers
- Principal investigator: Harris, Hannah Marie — Columbia University Health Sciences
- Study coordinator: Harris, Hannah Marie
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.