Investigating how regulatory T cells affect Alzheimer's disease
Official title: The Role of Regulatory T Cells in Alzheimer's Disease
Funded at University of Minnesota · NIH-10824927 · Data updated 2026-11-12
This study is looking at how certain immune cells, called regulatory T cells, might influence the progression of Alzheimer's disease in older adults, and it hopes to find new ways to help manage the condition by tracking patients' immune responses and thinking abilities over time.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project start | August 1, 2024 |
| Project end | July 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $53,974 |
| NIH project number | 1F30AG085982-01 |
| Project ID | NIH-10824927 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation include individuals aged 65 and older who are diagnosed with Alzheimer's disease or exhibit early symptoms of dementia.
✕Less likely to help
Patients with other forms of dementia or those under 65 years of age may not benefit from this research.
What this research studies
This research explores the role of regulatory T cells in the progression of Alzheimer's disease, a condition that primarily affects older adults. By examining the relationship between these immune cells and the neuroinflammation associated with Alzheimer's, the study aims to uncover potential therapeutic targets. Patients may be involved in assessments that monitor their immune response and cognitive function over time, contributing to a better understanding of the disease's mechanisms.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that slow the progression of Alzheimer's disease and improve the quality of life for patients.
How similar studies have gone: Previous research has shown promising results in targeting neuroinflammation in Alzheimer's disease, suggesting that this approach may yield beneficial outcomes.
Where this research is happening
-
University of Minnesota
Minneapolis, United States Active
Researchers
- Principal investigator: Hougard, Thomas R — University of Minnesota
- Study coordinator: Hougard, Thomas R
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.