Investigating how regulatory T cells affect Alzheimer's disease

The Role of Regulatory T Cells in Alzheimer's Disease

['FUNDING_FELLOWSHIP'] · UNIVERSITY OF MINNESOTA · NIH-10824927

This study is looking at how certain immune cells, called regulatory T cells, might influence the progression of Alzheimer's disease in older adults, and it hopes to find new ways to help manage the condition by tracking patients' immune responses and thinking abilities over time.

Quick facts

Phase['FUNDING_FELLOWSHIP']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF MINNESOTA (nih funded)
Locations1 site (MINNEAPOLIS, UNITED STATES)
Trial IDNIH-10824927 on ClinicalTrials.gov

What this research studies

This research explores the role of regulatory T cells in the progression of Alzheimer's disease, a condition that primarily affects older adults. By examining the relationship between these immune cells and the neuroinflammation associated with Alzheimer's, the study aims to uncover potential therapeutic targets. Patients may be involved in assessments that monitor their immune response and cognitive function over time, contributing to a better understanding of the disease's mechanisms.

Who could benefit from this research

Good fit: Ideal candidates for participation include individuals aged 65 and older who are diagnosed with Alzheimer's disease or exhibit early symptoms of dementia.

Not a fit: Patients with other forms of dementia or those under 65 years of age may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new treatments that slow the progression of Alzheimer's disease and improve the quality of life for patients.

How similar studies have performed: Previous research has shown promising results in targeting neuroinflammation in Alzheimer's disease, suggesting that this approach may yield beneficial outcomes.

Where this research is happening

MINNEAPOLIS, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.