Investigating how reducing nicotine levels in e-cigarettes affects addiction and health in users
Assessing the effect of nicotine reduction on ENDS user's addiction and exposures
['FUNDING_R01'] · FLORIDA INTERNATIONAL UNIVERSITY · NIH-10689848
This study is looking at how using e-cigarettes with lower nicotine levels affects people's addiction and health, so if you use e-cigarettes, your experience could help us understand if less nicotine is better for you.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | FLORIDA INTERNATIONAL UNIVERSITY (nih funded) |
| Locations | 1 site (MIAMI, UNITED STATES) |
| Trial ID | NIH-10689848 on ClinicalTrials.gov |
What this research studies
This research examines the impact of lowering nicotine levels in electronic nicotine delivery systems (ENDS), such as e-cigarettes, on users' addiction and health outcomes. By comparing users of high-nicotine ENDS with those using reduced nicotine options, the study aims to understand how different nicotine levels influence dependence, satisfaction, and exposure to harmful substances. Participants will undergo clinical assessments to measure various health indicators, including lung function and symptoms. The goal is to provide evidence that could inform regulatory strategies for reducing nicotine addiction among young users.
Who could benefit from this research
Good fit: Ideal candidates for this research are current e-cigarette users aged 21 to 35 who are using high-nicotine products.
Not a fit: Patients who do not use e-cigarettes or are outside the age range of 21 to 35 may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to effective strategies for reducing nicotine dependence and improving health outcomes for e-cigarette users.
How similar studies have performed: Previous research has shown that nicotine reduction strategies can be effective in decreasing dependence and improving health outcomes, suggesting a promising avenue for this study.
Where this research is happening
MIAMI, UNITED STATES
- FLORIDA INTERNATIONAL UNIVERSITY — MIAMI, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MAZIAK, WASIM — FLORIDA INTERNATIONAL UNIVERSITY
- Study coordinator: MAZIAK, WASIM
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.