Investigating how redox switches affect heart health and disease.
Basic and Translational Studies in Redox Regulation of Cardiovascular Physiology and Disease
This study is looking at how certain enzymes in your heart and blood vessels work, with the hope of finding new ways to treat heart diseases that could help patients like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project ID | NIH-11001171 on NIH RePORTER |
What this research studies
This research focuses on understanding the role of specific enzymes, known as redox switches, in the cardiovascular system. By studying how these enzymes interact with various substrates and signaling pathways, the researchers aim to uncover their functions in heart cells and blood vessels. The project involves advanced techniques, including genetically modified proteins and analysis of large human data sets, to explore the genetic factors that may influence cardiovascular health. Patients may benefit from insights that could lead to new treatments for heart diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with cardiovascular diseases or those at risk due to genetic factors.
Not a fit: Patients with non-cardiovascular related health issues may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic strategies for treating cardiovascular diseases.
How similar studies have performed: Other research has shown promising results in understanding redox signaling in cardiovascular health, indicating potential for success in this area.
Where this research is happening
Pittsburgh, United States
- University of Pittsburgh at Pittsburgh — Pittsburgh, United States (Active)
Researchers
- Principal investigator: Straub, Adam Carl — University of Pittsburgh at Pittsburgh
- Study coordinator: Straub, Adam Carl
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.