NIH-funded research R01 grant

Investigating how race, ethnicity, and environmental factors contribute to dementia and stroke disparities.

Official title: Race/ethnicity and Environmental Stressors: POtential drivers of Dementia and stroke inequities RESPOnD

Funded at Boston University Medical Campus · NIH-10977266 · Data updated 2026-11-12

This study is looking at how things like air pollution and neighborhood conditions might affect the risk of Alzheimer's and related dementias in older Black and Latino adults, with the hope of finding ways to help keep their minds healthy.

More Stroke research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionBoston University Medical Campus
NIH-funded
Lab location1 site (Boston, United States)
Project startJuly 15, 2024
Project endJune 30, 2029
Funding year2024
Award (this year)$837,826
NIH project number1R01NS139186-01
Project IDNIH-10977266 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are older Black and Latino adults who may be at risk for Alzheimer's disease-related dementias.

Less likely to help

Patients who do not belong to the targeted racial or ethnic groups or who are under 21 years old may not benefit from this research.

What this research studies

This research explores the connection between environmental stressors and the increased risk of Alzheimer's disease-related dementias (ADRD) among older Black and Latino adults. It focuses on how factors like air pollution, access to green spaces, and neighborhood conditions may influence vascular risk factors for ADRD. By analyzing data from diverse cohorts over a long period, the study aims to understand the combined effects of these environmental exposures on cognitive health. The goal is to identify potential interventions that could mitigate these risks.

Why it matters

Potential benefit: If successful, this research could lead to targeted strategies for reducing dementia and stroke risks in vulnerable populations.

How similar studies have gone: Previous research has shown that environmental factors significantly impact health outcomes, suggesting that this approach could yield valuable insights.

Where this research is happening

  • Boston University Medical Campus
    Boston, United States
    Active

Researchers

  • Principal investigator: Pescador Jimenez, Marcia Ixchel — Boston University Medical Campus
  • Study coordinator: Pescador Jimenez, Marcia Ixchel

Related research

Other NIH-funded projects on the same topics.

  • BBB Dysfunction after Stroke and Risk for Dementia

    A study at Stanford will look at whether inflammation after a stroke leads to leaky blood vessels and later dementia, by following stroke survivors and comparing them with people without stroke.

    NIH research Stanford University · Stanford, United States · NIH-11610460

  • DNMT3a and oligodendrocyte renewal after stroke

    A patient-focused study will explore how a specific gene, DNMT3a, might help repair brain white matter after a stroke to reduce dementia risk.

    NIH research Massachusetts General Hospital · Boston, United States · NIH-11462831

  • BBB Dysfunction after Stroke and Dementia Risk

    This NIH grant aims to understand why some people develop dementia years after a stroke by looking at brain inflammation and blood vessel leakage.

    NIH research Stanford University · Stanford, United States · NIH-11395559

  • Leaky brain blood vessels after stroke linked to dementia

    This work looks for MRI signs and blood markers of leaky blood vessels and inflammation in people who had a stroke years ago and may be at risk for memory and thinking problems.

    NIH research Stanford University · Stanford, United States · NIH-11395026

  • Understanding and reducing cognitive problems after stroke

    A study from the University of Michigan aims to see if simple cognitive activities and sleep improvements can lower the risk of developing vascular cognitive impairment and dementia after stroke.

    NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11384379

  • Post-stroke cognitive decline and dementia: understanding and preventing PSCID

    A large NIH project will use real-world data from two million stroke records to better understand how many people develop PSCID and what factors raise that risk, with the goal of guiding prevention and care.

    NIH research Ut Southwestern Medical Center · Dallas, United States · NIH-11382953

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.