Investigating how race and ethnicity affect Alzheimer's disease risk across generations
Add Health Parent Study: A Biosocial Resource for the Study of Multigenerational Racial/Ethnic Disparities in Alzheimer's Disease and Alzheimer's Disease-Related Dementias (AD/ADRD)
This study is looking at how family history and background can affect the risk of Alzheimer's and related memory issues in different racial and ethnic groups, and it’s for people who want to help us understand these differences better by sharing their experiences and providing some health information.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project ID | NIH-11079634 on NIH RePORTER |
What this research studies
This research focuses on understanding the intergenerational factors that influence the risk of Alzheimer's Disease and related dementias (AD/ADRD) among different racial and ethnic groups. By collecting social, behavioral, and biological data from parents of a national cohort, the study aims to identify disparities in cognitive aging and AD/ADRD risk. Participants will undergo cognitive assessments and provide DNA samples, allowing researchers to analyze how these factors vary across diverse populations. The study seeks to fill significant knowledge gaps regarding the impact of race and ethnicity on Alzheimer's risk.
Who could benefit from this research
Good fit: Ideal candidates for participation include non-Hispanic Black and Hispanic parents aged 58-90 who have previously participated in the Add Health study.
Not a fit: Patients who do not belong to the specified racial or ethnic groups or who are outside the age range may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and targeted interventions for Alzheimer's disease risk among diverse populations.
How similar studies have performed: Previous research has shown success in studying health disparities related to Alzheimer's disease, making this approach both relevant and promising.
Where this research is happening
Chapel Hill, United States
- Univ of North Carolina Chapel Hill — Chapel Hill, United States (Active)
Researchers
- Principal investigator: Harris, Kathleen Mullan — Univ of North Carolina Chapel Hill
- Study coordinator: Harris, Kathleen Mullan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.