Investigating how race affects the development of pancreatic cancer.
Full Project 3
This study is looking at how early changes in pancreatic cells can lead to a serious type of cancer called pancreatic ductal adenocarcinoma, and it aims to understand how these changes vary among different racial groups, especially to help improve prevention and treatment for Black individuals.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Southern California NIH-funded |
| Lab location | 1 site (Los Angeles, UNITED STATES) |
| Project ID | NIH-10932246 on NIH RePORTER |
What this research studies
This research focuses on understanding the early changes in pancreatic cells that can lead to pancreatic ductal adenocarcinoma (PDAC), a highly aggressive form of cancer. The study aims to explore how these changes, known as acinar-to-ductal metaplasia (ADM), differ among racial groups, particularly among Black, White, and Hispanic individuals. By analyzing both normal and diseased pancreatic tissues, the research seeks to uncover the cellular and molecular mechanisms that contribute to the higher incidence of PDAC in Black populations. This could lead to better prevention strategies and treatments tailored to different racial groups.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals from Black, White, and Hispanic backgrounds who may be at risk for pancreatic cancer or have a history of chronic pancreatitis.
Not a fit: Patients who do not belong to the racial groups being studied or those without risk factors for pancreatic cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for pancreatic cancer, particularly for Black individuals who are disproportionately affected.
How similar studies have performed: Previous research has indicated significant racial differences in the development of pancreatic cancer, suggesting that this approach could yield valuable insights.
Where this research is happening
Los Angeles, UNITED STATES
- University of Southern California — Los Angeles, United States (Active)
Researchers
- Principal investigator: Han, Bo — University of Southern California
- Study coordinator: Han, Bo
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.