Investigating how race affects pancreatic cancer development
Racial contributions of microenvironment remolding during pancreatic metaplasia
['FUNDING_OTHER'] · FLORIDA AGRICULTURAL AND MECHANICAL UNIV · NIH-10931525
This study is looking at how racial differences might affect the early changes in the pancreas that can lead to pancreatic cancer, focusing on tissues from Black, White, and Hispanic donors to help find better ways to prevent and treat this disease, especially for those at higher risk.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | FLORIDA AGRICULTURAL AND MECHANICAL UNIV (nih funded) |
| Locations | 1 site (TALLAHASSEE, UNITED STATES) |
| Trial ID | NIH-10931525 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding how racial differences influence the process of acinar-to-ductal metaplasia (ADM), which is a key early event in the development of pancreatic ductal adenocarcinoma (PDAC). By examining pancreatic tissues from Black, White, and Hispanic donors, the study aims to uncover the cellular and molecular mechanisms that contribute to the higher incidence of PDAC in Black populations. The research will utilize both normal and diseased pancreatic tissues to provide a comprehensive view of how race impacts ADM and its progression to cancer. This could lead to targeted prevention strategies and treatments for those at higher risk.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals from Black, White, and Hispanic backgrounds who are at risk for or have been diagnosed with pancreatic conditions.
Not a fit: Patients who do not belong to the racial groups being studied or those without pancreatic conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for pancreatic cancer, particularly for Black patients who are disproportionately affected.
How similar studies have performed: Previous research has indicated significant racial differences in pancreatic cancer development, suggesting that this approach could yield valuable insights.
Where this research is happening
TALLAHASSEE, UNITED STATES
- FLORIDA AGRICULTURAL AND MECHANICAL UNIV — TALLAHASSEE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: ALI, JAMEL — FLORIDA AGRICULTURAL AND MECHANICAL UNIV
- Study coordinator: ALI, JAMEL
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.