Investigating how PTSD treatments affect heart disease risk
Official title: Evidence-based Treatment for PTSD and Cardiovascular Disease Risk
Funded at University of California Los Angeles · NIH-11028141 · Data updated 2026-11-12
This study is looking at how different treatments for PTSD might help lower the chances of heart problems in veterans, using health records from over 2 million people to see which therapies work best.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project start | February 1, 2025 |
| Project end | November 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $732,672 |
| NIH project number | 1R01HL176899-01 |
| Project ID | NIH-11028141 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are veterans diagnosed with PTSD who are receiving treatment through the Department of Veterans Affairs healthcare system.
✕Less likely to help
Patients who do not have PTSD or those who are not veterans may not receive any benefit from this research.
What this research studies
This research explores the relationship between treatments for posttraumatic stress disorder (PTSD) and the risk of developing cardiovascular disease (CVD). By utilizing a comprehensive database of over 2 million veterans, the study will analyze electronic health records to assess the effectiveness of evidence-based psychotherapies and antidepressants in reducing CVD incidence and mortality among PTSD patients. The approach includes advanced data analysis techniques and natural language processing to evaluate treatment outcomes and health impacts over time.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies that not only alleviate PTSD symptoms but also reduce the risk of cardiovascular disease in affected individuals.
How similar studies have gone: Previous research has shown that effective PTSD treatments can improve overall health outcomes, suggesting potential for success in this novel approach.
Where this research is happening
-
University of California Los Angeles
Los Angeles, United States Active
Researchers
- Principal investigator: Sumner, Jennifer a — University of California Los Angeles
- Study coordinator: Sumner, Jennifer a
Related research
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-
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-
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.