Investigating how proteins in cells interact and are labeled for advanced imaging
Labeling cellular proteins for multi-scale microscopy and other applications
['FUNDING_OTHER'] · OREGON HEALTH & SCIENCE UNIVERSITY · NIH-10929939
This study is working on new ways to tag and visualize proteins in cells so that scientists can see how they work together over time, which could help improve our understanding and treatment of diseases.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | OREGON HEALTH & SCIENCE UNIVERSITY (nih funded) |
| Locations | 1 site (PORTLAND, UNITED STATES) |
| Trial ID | NIH-10929939 on ClinicalTrials.gov |
What this research studies
This research focuses on developing innovative technologies to label and image cellular proteins, allowing scientists to observe how these proteins organize and interact over time. By utilizing principles of chemical biology, the team aims to create new genetic tags that can be used in various microscopy techniques, including fluorescence and electron microscopy. These advancements will enable researchers to study the molecular basis of diseases with unprecedented detail, potentially leading to better understanding and treatment options. The project addresses current limitations in protein labeling methods, aiming to enhance multi-scale microscopy capabilities.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions that involve protein interactions and organization, such as certain genetic disorders or cancers.
Not a fit: Patients with conditions unrelated to protein interactions or those who do not require advanced imaging techniques may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding diseases at the molecular level, improving diagnosis and treatment strategies.
How similar studies have performed: Other research has shown success in developing advanced imaging techniques, but this approach with VIP tags is innovative and represents a novel advancement in the field.
Where this research is happening
PORTLAND, UNITED STATES
- OREGON HEALTH & SCIENCE UNIVERSITY — PORTLAND, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BEATTY, KIMBERLY ELIZABETH — OREGON HEALTH & SCIENCE UNIVERSITY
- Study coordinator: BEATTY, KIMBERLY ELIZABETH
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.