Investigating how proteins in cells interact and are labeled for advanced imaging
Official title: Labeling cellular proteins for multi-scale microscopy and other applications
Funded at Oregon Health & Science University · NIH-10929939 · Data updated 2026-11-12
This study is working on new ways to tag and visualize proteins in cells so that scientists can see how they work together over time, which could help improve our understanding and treatment of diseases.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oregon Health & Science University NIH-funded |
| Lab location | 1 site (Portland, United States) |
| Project start | September 18, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $385,000 |
| NIH project number | 5R35GM149559-02 |
| Project ID | NIH-10929939 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions that involve protein interactions and organization, such as certain genetic disorders or cancers.
✕Less likely to help
Patients with conditions unrelated to protein interactions or those who do not require advanced imaging techniques may not benefit from this research.
What this research studies
This research focuses on developing innovative technologies to label and image cellular proteins, allowing scientists to observe how these proteins organize and interact over time. By utilizing principles of chemical biology, the team aims to create new genetic tags that can be used in various microscopy techniques, including fluorescence and electron microscopy. These advancements will enable researchers to study the molecular basis of diseases with unprecedented detail, potentially leading to better understanding and treatment options. The project addresses current limitations in protein labeling methods, aiming to enhance multi-scale microscopy capabilities.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding diseases at the molecular level, improving diagnosis and treatment strategies.
How similar studies have gone: Other research has shown success in developing advanced imaging techniques, but this approach with VIP tags is innovative and represents a novel advancement in the field.
Where this research is happening
-
Oregon Health & Science University
Portland, United States Active
Researchers
- Principal investigator: Beatty, Kimberly Elizabeth — Oregon Health & Science University
- Study coordinator: Beatty, Kimberly Elizabeth
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.