Investigating how prenatal inflammation affects brain development in children up to age 9.
Examining Prenatal Inflammation and Neurodevelopment in a Longitudinal Fetal-to-Age 9 Imaging Study
This study is looking at how inflammation during pregnancy might affect how a child's brain develops, and it's for families with kids from pregnancy up to age 9, as researchers want to understand if this inflammation could lead to issues like ADHD or autism.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11042190 on NIH RePORTER |
What this research studies
This research examines the impact of inflammation during pregnancy on the brain development of children. By studying a group of children from fetal stages through age 9, the researchers will analyze how prenatal inflammation influences neural connections and may increase the risk of developmental disorders like ADHD and autism. The study utilizes advanced imaging techniques and tooth-biomarker assays to explore the relationship between prenatal factors and neurodevelopmental outcomes. Participants will undergo MRI scans and provide tooth samples to help identify protective factors that may mitigate negative effects.
Who could benefit from this research
Good fit: Ideal candidates for this research are pregnant individuals and their children, particularly those at risk for neurodevelopmental disorders.
Not a fit: Patients who are not pregnant or whose children are older than 9 years may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and prevention strategies for neurodevelopmental disorders in children.
How similar studies have performed: Previous research has shown promising results in understanding the effects of prenatal factors on child development, but this specific approach is relatively novel.
Where this research is happening
New York, United States
- New York University School of Medicine — New York, United States (Active)
Researchers
- Principal investigator: Thomason, Moriah E — New York University School of Medicine
- Study coordinator: Thomason, Moriah E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.