Investigating how prenatal experiences affect child brain development
5/6 HBCD Prenatal Experiences and Longitudinal Development (PRELUDE) Consortium
This study is looking at how being exposed to substances like opioids before birth, along with other environmental factors, affects how children's brains develop from birth through childhood, and it's for families who want to understand more about their child's growth and development.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project ID | NIH-10884383 on NIH RePORTER |
What this research studies
This research focuses on understanding how prenatal exposure to substances like opioids, along with environmental factors, influences brain development in children from birth through childhood. By utilizing advanced neuroimaging techniques, the study aims to identify typical brain development trajectories and how they may differ in children exposed to substances in utero. The research involves collaboration among six prominent medical centers, ensuring a comprehensive approach to data collection and analysis. Participants will be monitored over time to assess their cognitive, social, and emotional development.
Who could benefit from this research
Good fit: Ideal candidates for this research include pregnant women who have been exposed to opioids or other substances and their children.
Not a fit: Patients who are not pregnant or whose children are not exposed to substances during pregnancy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and interventions for children affected by prenatal substance exposure.
How similar studies have performed: Previous research has shown promising results in understanding brain development through neuroimaging, but this specific approach focusing on high-risk populations is relatively novel.
Where this research is happening
Chapel Hill, United States
- Univ of North Carolina Chapel Hill — Chapel Hill, United States (Active)
Researchers
- Principal investigator: Lin, Weili — Univ of North Carolina Chapel Hill
- Study coordinator: Lin, Weili
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.