Investigating how prenatal experiences affect child brain development

1/6 HBCD Prenatal Experiences and Longitudinal Development (PRELUDE) Consortium

NIH-funded research Arkansas Children's Hospital Res Inst · NIH-10877068

This study is looking at how being exposed to substances like opioids before birth affects how children's brains grow and develop, and it's for families who want to understand the potential impacts on their child's social and emotional skills as they grow up.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionArkansas Children's Hospital Res Inst NIH-funded
Lab location1 site (Little Rock, United States)
Project IDNIH-10877068 on NIH RePORTER

What this research studies

This research focuses on understanding the impact of prenatal exposure to substances like opioids on brain development in children. By utilizing advanced neuroimaging techniques, the study aims to track brain development from birth through childhood, considering various biological and environmental factors. The research involves collaboration among six prominent medical centers to gather comprehensive data on child social, cognitive, and emotional outcomes. It seeks to clarify how different prenatal experiences influence brain trajectories and developmental outcomes in children.

Who could benefit from this research

Good fit: Ideal candidates for participation include pregnant women who have been exposed to opioids or other substances, as well as their children from birth to age 11.

Not a fit: Patients who are not pregnant or whose children are older than 11 years may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and interventions for children affected by prenatal substance exposure.

How similar studies have performed: Previous research using neuroimaging to study brain development in high-risk populations has shown promising results, indicating the potential for significant findings in this area.

Where this research is happening

Little Rock, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.