Investigating how prediabetes affects blood clotting in veterans
Official title: Thrombotic Susceptibility in Veterans: Influence of prediabetes
Funded at Iowa City VA Medical Center · NIH-11051607 · Data updated 2026-11-12
This study is looking at how prediabetes might raise the chances of blood clots, which can lead to heart attacks and strokes, especially in veterans, and aims to find ways to help reduce these risks.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Iowa City VA Medical Center NIH-funded |
| Lab location | 1 site (Iowa City, United States) |
| Project start | July 1, 2020 |
| Project end | March 31, 2029 |
| Funding year | 2025 |
| NIH project number | 2I01BX007087-06A1 |
| Project ID | NIH-11051607 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are young and middle-aged veterans who are prediabetic or at risk of developing prediabetes.
✕Less likely to help
Patients who are not veterans or those without prediabetes may not benefit from this research.
What this research studies
This research focuses on understanding how prediabetes may increase the risk of blood clotting complications, such as heart attacks and strokes, particularly in veterans. The study aims to explore the underlying mechanisms that lead to heightened thrombotic susceptibility in young and middle-aged veterans with prediabetes. By examining platelet activity and the role of mitochondrial reactive oxygen species, the research seeks to identify potential interventions that could mitigate these risks. The findings could provide valuable insights into preventing serious health issues in this population.
Why it matters
Potential benefit: If successful, this research could lead to improved prevention strategies for thrombotic events in veterans with prediabetes.
How similar studies have gone: Previous research has indicated a link between prediabetes and increased thrombotic risk, suggesting that this approach has potential for significant findings.
Where this research is happening
-
Iowa City VA Medical Center
Iowa City, United States Active
Researchers
- Principal investigator: Dayal, Sanjana — Iowa City VA Medical Center
- Study coordinator: Dayal, Sanjana
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.