Investigating how potassium in cerebrospinal fluid supports brain development and function
Official title: How cerebrospinal fluid (CSF) potassium supports brain development and activity
Funded at Stanford University · NIH-10872934 · Data updated 2026-11-12
This study is looking at how the amount of potassium in the fluid around your brain affects its growth and function, which could help us understand brain health and conditions that arise when this balance is off.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project start | September 1, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $673,189 |
| NIH project number | 1R01MH136258-01 |
| Project ID | NIH-10872934 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals under 21 years old, particularly those with neurodevelopmental conditions such as autism spectrum disorder.
✕Less likely to help
Patients over 21 years old or those without neurodevelopmental concerns may not benefit from this research.
What this research studies
This research explores the role of potassium levels in cerebrospinal fluid (CSF) and how they influence brain development and activity. By examining changes in CSF potassium concentrations during critical developmental stages, the study aims to understand their impact on brain cell growth, maintenance, and overall health. The research utilizes advanced techniques to manipulate CSF potassium levels and assess the resulting effects on neurodevelopmental processes. This could provide insights into various neurological conditions associated with abnormal CSF composition.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for promoting healthy brain development and treating neurodevelopmental disorders.
How similar studies have gone: Previous research has shown promising results in understanding the role of ions in brain development, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Stanford University
Stanford, United States Active
Researchers
- Principal investigator: Fame, Ryan Marie — Stanford University
- Study coordinator: Fame, Ryan Marie
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.