Investigating how placental factors affect kidney function in preeclampsia
Extracellular Vesicles as a Link Between Placental and Renal Dysfunction in Preeclampsia
['FUNDING_OTHER'] · UNIVERSITY OF CALIFORNIA, SAN DIEGO · NIH-10675564
This study is looking at how problems with the placenta might affect kidney health in women with preeclampsia, and by analyzing urine samples, researchers hope to find helpful markers that could improve diagnosis and treatment for this condition.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN DIEGO (nih funded) |
| Locations | 1 site (LA JOLLA, UNITED STATES) |
| Trial ID | NIH-10675564 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding the connection between placental dysfunction and kidney issues in women with preeclampsia, a serious pregnancy-related condition. By examining extracellular vesicles released from the placenta, the study aims to identify specific RNA and protein markers that may indicate renal impairment associated with preeclampsia. The approach involves collecting urine samples from participants to analyze these vesicles, which could lead to better diagnostic tools and treatment strategies. The goal is to enhance personalized medicine approaches for managing preeclampsia and its complications.
Who could benefit from this research
Good fit: Ideal candidates for this research are pregnant women diagnosed with preeclampsia or at risk of developing the condition.
Not a fit: Patients who are not pregnant or those without a diagnosis of preeclampsia are unlikely to benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnosis and treatment options for women suffering from preeclampsia, potentially reducing maternal and fetal morbidity and mortality.
How similar studies have performed: While the investigation of extracellular vesicles in preeclampsia is a relatively novel approach, similar studies have shown promise in other conditions, indicating potential for success.
Where this research is happening
LA JOLLA, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN DIEGO — LA JOLLA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PANTHAM, PRIYADARSHINI — UNIVERSITY OF CALIFORNIA, SAN DIEGO
- Study coordinator: PANTHAM, PRIYADARSHINI
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.