Investigating how physical activity affects muscle strength in children with chronic kidney disease.
Official title: Physical Activity and Muscle Strength in Pediatric CKD
Funded at Children's Hosp of Philadelphia · NIH-11030785 · Data updated 2026-11-12
This study is looking at how getting more active can help kids and teens with chronic kidney disease stay strong and healthy, and it will use a fun online program to encourage them to add 15 extra minutes of activity each day over 12 weeks.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Children's Hosp of Philadelphia NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | February 7, 2024 |
| Project end | December 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $182,197 |
| NIH project number | 5K23DK134847-02 |
| Project ID | NIH-11030785 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children and adolescents aged 0-21 years diagnosed with chronic kidney disease.
✕Less likely to help
Patients who are not diagnosed with chronic kidney disease or are outside the age range of 0-21 years may not benefit from this research.
What this research studies
This research focuses on children and adolescents with chronic kidney disease (CKD) and aims to understand the relationship between physical activity, muscle strength, and cardiovascular disease risk. The study will implement a 12-week physical activity intervention designed to increase daily activity levels by 15 minutes, using a web-based platform to facilitate participation. By analyzing the effects of this intervention, the research seeks to identify effective strategies to enhance physical activity and improve health outcomes in this vulnerable population.
Why it matters
Potential benefit: If successful, this research could lead to improved physical activity levels and muscle strength in children with CKD, potentially reducing their risk of cardiovascular disease.
How similar studies have gone: Previous research has shown that physical activity interventions can be beneficial for improving health outcomes in pediatric populations, suggesting a promising approach for this study.
Where this research is happening
-
Children's Hosp of Philadelphia
Philadelphia, United States Active
Researchers
- Principal investigator: Kogon, Amy — Children's Hosp of Philadelphia
- Study coordinator: Kogon, Amy
Related research
Other NIH-funded projects on the same topics.
-
Time-Efficient Breathing Muscle Training to Help Sleep and Blood Pressure in Midlife Women
A short, easy-to-do breathing muscle program is tested to help sleep and lower nervous system activity in middle-aged women with hot flashes.
-
Breathing-strength training to lower blood pressure and help blood vessel health in postmenopausal women
This compares a short daily high-resistance breathing exercise to standard aerobic workouts to help lower blood pressure and improve blood vessel health in postmenopausal women.
-
Time-efficient inspiratory muscle training to help blood pressure in adults with type 1 diabetes
A small, home-based breathing training program done in five minutes daily aims to lower systolic blood pressure for adults with type 1 diabetes.
-
Donepezil’s effect on aging muscles and resilience
A patient-friendly look at how a drug used for memory problems might help aging muscles stay stronger and more resilient.
-
Using a smartphone app to help strengthen breathing muscles and lower blood pressure
This study is testing a smartphone app that helps people do breathing exercises at home to strengthen their breathing muscles and lower blood pressure, and it's for anyone looking to improve their heart health.
-
Breathing Exercises to Lower Blood Pressure in Adults with Kidney Disease
This project explores whether a special type of breathing exercise can help midlife and older adults with chronic kidney disease manage their high blood pressure.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.