Investigating how phthalate exposure affects women's reproductive aging
Official title: Phthalate Exposure and Female Reproductive Aging
Funded at University of Illinois at Urbana-Champaign · NIH-11226341 · Data updated 2026-11-12
This study is looking at how certain chemicals in our environment, called phthalates, might affect how quickly the female reproductive system ages, which could lead to fertility issues and health risks, and it’s using female mice to help us understand these effects better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Illinois at Urbana-Champaign NIH-funded |
| Lab location | 1 site (Champaign, United States) |
| Project start | December 1, 2022 |
| Project end | October 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $71,628 |
| NIH project number | 3R01ES034112-03S1 |
| Project ID | NIH-11226341 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are women aged 21 and older who may be concerned about reproductive health and aging.
✕Less likely to help
Patients who are not affected by reproductive aging or those who are not exposed to phthalates may not benefit from this research.
What this research studies
This research focuses on understanding how exposure to certain environmental chemicals, specifically phthalates, impacts the aging of the female reproductive system. It aims to identify the mechanisms behind early reproductive aging, which can lead to infertility and increased health risks. The study will analyze the effects of these chemicals on inflammation and reproductive health in female mice, providing insights that could be relevant to human health. By examining gene expression and inflammatory responses, the research seeks to uncover critical factors that contribute to reproductive aging.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and prevention strategies for early reproductive aging in women.
How similar studies have gone: Previous studies have shown that environmental chemicals can impact reproductive health, suggesting that this research could build on established findings.
Where this research is happening
-
University of Illinois at Urbana-Champaign
Champaign, United States Active
Researchers
- Principal investigator: Flaws, Jodi a. — University of Illinois at Urbana-Champaign
- Study coordinator: Flaws, Jodi a.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.