Investigating how Perilipin 5 affects fat tissue function
Perilipin 5 in the Regulation of Adipose Tissue Function
['FUNDING_R01'] · UT SOUTHWESTERN MEDICAL CENTER · NIH-10913605
This study is looking at a protein called Perilipin 5 to see how it helps manage fat in our bodies, which could lead to new treatments for obesity and type 2 diabetes by finding ways to activate fat cells that burn energy.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UT SOUTHWESTERN MEDICAL CENTER (nih funded) |
| Locations | 1 site (DALLAS, UNITED STATES) |
| Trial ID | NIH-10913605 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding the role of Perilipin 5 in regulating adipose tissue, which is crucial for managing energy balance and combating obesity and type 2 diabetes. The study aims to explore how activating brown and beige fat cells can help dissipate excess energy and improve metabolic health. By examining the interactions of Perilipin 5 with other proteins, the research seeks to develop new pharmacological strategies that could lead to effective treatments for obesity-related disorders. Patients may benefit from insights that could lead to innovative therapies targeting fat metabolism.
Who could benefit from this research
Good fit: Ideal candidates for this research include adults struggling with obesity or type 2 diabetes who are looking for new treatment options.
Not a fit: Patients who are not overweight or do not have metabolic disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that help reduce obesity and improve metabolic health in patients.
How similar studies have performed: Previous research has shown promising results in activating brown fat for metabolic benefits, suggesting that this approach could be effective.
Where this research is happening
DALLAS, UNITED STATES
- UT SOUTHWESTERN MEDICAL CENTER — DALLAS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BICKEL, PERRY E — UT SOUTHWESTERN MEDICAL CENTER
- Study coordinator: BICKEL, PERRY E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Adult-Onset Diabetes Mellitus