Investigating how people use both combustible and electronic cigarettes to help quit smoking

Dual use of combustible and electronic cigarettes: A fine-grained naturalistic cohort study to investigate dynamic use patterns and trajectories that lead to smoking cessation

NIH-funded research Medical University of South Carolina · NIH-11124145

This study is looking at people who smoke regular cigarettes and use e-cigarettes to see how they switch between the two and if it helps them quit smoking for good, with the goal of finding better ways to support those trying to stop.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMedical University of South Carolina NIH-funded
Lab location1 site (Charleston, United States)
Project IDNIH-11124145 on NIH RePORTER

What this research studies

This research examines the patterns and behaviors of individuals who use both combustible cigarettes and electronic cigarettes. By following a cohort of participants over time, the study aims to understand how these dual users transition between products and whether this affects their ability to quit smoking altogether. The research will collect detailed data on daily usage patterns to identify factors that contribute to successful cessation or continued use. This information could help inform treatment strategies and public health policies regarding tobacco use.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 21 and older who currently use both combustible and electronic cigarettes.

Not a fit: Patients who exclusively use either combustible cigarettes or electronic cigarettes without dual use may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for helping individuals quit smoking by understanding the dynamics of dual tobacco product use.

How similar studies have performed: While there have been studies on tobacco use, this research focuses specifically on the dual use of combustible and electronic cigarettes, making it a novel approach.

Where this research is happening

Charleston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions cancer preventionCancers
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.