Investigating how partial dysfunction of the vestibular system affects sensory processing.
Peripheral vestibular hypofunction and neurosensory coding
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA LOS ANGELES · NIH-11082283
This study is looking at how problems with the balance system in the inner ear affect movement and coordination, using animals to learn more about the condition, which could help doctors find better ways to diagnose and treat people with balance issues.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA LOS ANGELES (nih funded) |
| Locations | 1 site (LOS ANGELES, UNITED STATES) |
| Trial ID | NIH-11082283 on ClinicalTrials.gov |
What this research studies
This research explores the mechanisms behind peripheral vestibular hypofunction, a condition where the vestibular sensory system does not function properly. Using an animal model, the study induces controlled damage to the vestibular system and examines the resulting physiological changes through advanced techniques like electrophysiology and histopathology. By correlating these changes with behavioral tests, the research aims to better understand how vestibular dysfunction impacts balance and spatial orientation. This could lead to improved diagnostic and therapeutic strategies for patients with vestibular disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing symptoms of vestibular dysfunction, such as dizziness, imbalance, or vertigo.
Not a fit: Patients with vestibular disorders not related to peripheral vestibular hypofunction may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better treatments and interventions for individuals suffering from balance disorders related to vestibular dysfunction.
How similar studies have performed: Previous research has shown promising results in understanding vestibular dysfunction through similar methodologies, indicating a potential for success in this approach.
Where this research is happening
LOS ANGELES, UNITED STATES
- UNIVERSITY OF CALIFORNIA LOS ANGELES — LOS ANGELES, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HOFFMAN, LARRY F — UNIVERSITY OF CALIFORNIA LOS ANGELES
- Study coordinator: HOFFMAN, LARRY F
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.