Investigating how oxygen levels affect a new type of radiation therapy
Oxygen Dynamics in FLASH Radiotherapy
This study is looking at a new type of radiation therapy called FLASH-RT to see how it affects oxygen levels in tissues, with the goal of finding ways to better treat cancer while protecting healthy cells.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Dartmouth College NIH-funded |
| Lab location | 1 site (Hanover, United States) |
| Project ID | NIH-11318679 on NIH RePORTER |
What this research studies
This research explores the effects of ultra-high dose rate radiation therapy, known as FLASH-RT, on oxygen dynamics in tissues. By measuring oxygen levels with high precision, the study aims to understand how FLASH-RT can minimize damage to healthy tissues while effectively targeting tumors. The researchers will compare oxygen consumption during FLASH-RT to conventional radiation therapy to uncover the mechanisms behind the 'FLASH' effect. This could lead to improved treatment strategies for cancer patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are cancer patients undergoing radiation therapy who may benefit from reduced side effects.
Not a fit: Patients who are not receiving radiation therapy or those with conditions unrelated to cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and safer radiation therapy options for cancer patients.
How similar studies have performed: Previous research has shown promising results with similar approaches in radiation therapy, indicating potential for significant advancements.
Where this research is happening
Hanover, United States
- Dartmouth College — Hanover, United States (Active)
Researchers
- Principal investigator: Pogue, Brian William — Dartmouth College
- Study coordinator: Pogue, Brian William
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.