Investigating how opioid misuse affects HIV in the brain
Single Cell Transciptomics of the Opioid Use Disorder and HIV Syndemic in the Human Brain
This study is looking at how using opioids might make brain problems worse for people living with HIV, and it hopes to find new ways to help those who are dealing with both issues.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-10914802 on NIH RePORTER |
What this research studies
This research explores the impact of opioid misuse on HIV infection and its effects on the brain. By analyzing brain samples from patients, the study aims to understand how opioid use may worsen HIV-related neurological issues. The approach involves advanced techniques to examine specific cell types in the brain at a detailed level, providing insights into the relationship between opioid use and HIV pathogenesis. The findings could lead to better treatment strategies for individuals affected by both conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV who also have a history of opioid misuse.
Not a fit: Patients who do not have HIV or opioid use disorder may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for patients with HIV and opioid use disorder.
How similar studies have performed: Previous research has shown that understanding the interactions between substance use and viral infections can lead to significant advancements in treatment, suggesting this approach has potential for success.
Where this research is happening
La Jolla, United States
- University of California, San Diego — La Jolla, United States (Active)
Researchers
- Principal investigator: Cheng, Christine — University of California, San Diego
- Study coordinator: Cheng, Christine
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.