Investigating how obesity affects the risk of Alzheimer's disease across different ages and genders.

Addressing biases and evaluating gender differences in lifecourse obesity and risk of ADRD in a diverse cohort

NIH-funded research University of California at Davis · NIH-10994551

This study is looking at how being overweight at different ages might affect the chances of developing Alzheimer's and other memory problems, and it wants to hear from people about their health experiences to better understand this connection.

Quick facts

Grant typeFellowship grant
Study typeNIH-funded research
Funding institutionUniversity of California at Davis NIH-funded
Lab location1 site (Davis, United States)
Project IDNIH-10994551 on NIH RePORTER

What this research studies

This research examines the relationship between obesity at various life stages and the risk of Alzheimer's Disease and related dementias (ADRD). It focuses on understanding how obesity may act as a risk or protective factor for cognitive decline, particularly in diverse populations. By analyzing data from three well-characterized cohort studies, the research aims to address biases that may affect previous findings and provide a clearer picture of how obesity impacts brain health over time. Patients may be asked to share their health histories and participate in assessments to contribute to this important work.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals from diverse backgrounds, particularly African Americans, who are concerned about obesity and its impact on cognitive health.

Not a fit: Patients who are not affected by obesity or do not have concerns about Alzheimer's disease may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for preventing Alzheimer's disease and related dementias by identifying critical periods for obesity intervention.

How similar studies have performed: Previous research has shown that addressing modifiable risk factors like obesity can significantly impact health outcomes, suggesting that this approach may yield valuable insights.

Where this research is happening

Davis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer's disease and related dementia
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.