Investigating how obesity affects inflammation and brain health in children with multiple sclerosis
Obesity as a Driver of Inflammation and Brain Volume Loss in Pediatric Multiple Sclerosis
This study is looking at how being overweight might affect inflammation and brain health in kids with multiple sclerosis, and it aims to find ways to help improve their treatment and outcomes.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Virginia NIH-funded |
| Lab location | 1 site (Charlottesville, United States) |
| Project ID | NIH-10984972 on NIH RePORTER |
What this research studies
This research focuses on understanding the relationship between obesity and its impact on inflammation and brain volume loss in children diagnosed with multiple sclerosis (MS). The study will utilize advanced MRI techniques to assess brain changes and will involve multi-centered clinical studies to gather comprehensive data. By examining the role of obesity as a risk factor, the research aims to identify potential therapeutic targets and improve outcomes for pediatric MS patients. The principal investigator, Dr. Brenton, will collaborate with a team of experts to enhance the understanding of obesity's effects on brain health in this vulnerable population.
Who could benefit from this research
Good fit: Ideal candidates for this research are children and adolescents aged 12-20 who have been diagnosed with multiple sclerosis and may also be experiencing obesity.
Not a fit: Patients who do not have multiple sclerosis or are outside the age range of 12-20 may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies and interventions for children with multiple sclerosis, particularly those struggling with obesity.
How similar studies have performed: Previous research has indicated a connection between obesity and neurological conditions, suggesting that this approach may yield valuable insights, although the specific focus on pediatric MS is relatively novel.
Where this research is happening
Charlottesville, United States
- University of Virginia — Charlottesville, United States (Active)
Researchers
- Principal investigator: Brenton, James Nicholas — University of Virginia
- Study coordinator: Brenton, James Nicholas
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.