Investigating how obesity affects diverticulitis risk in women.

A prospective cohort study to determine the role of obesity in diverticulitis

NIH-funded research Univ of North Carolina Chapel Hill · NIH-11083685

This study is looking at how being overweight might affect the risk of diverticulitis in women after menopause, and it hopes to find new ways to help manage this condition by understanding the changes that happen in the body during this time.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniv of North Carolina Chapel Hill NIH-funded
Lab location1 site (Chapel Hill, United States)
Project IDNIH-11083685 on NIH RePORTER

What this research studies

This research focuses on understanding the relationship between obesity and diverticulitis, particularly in postmenopausal women who are at a higher risk for this condition. The study aims to explore how metabolic changes associated with menopause, such as increased visceral fat and insulin resistance, may contribute to the development of diverticulitis. By examining a cohort of participants, the researchers will gather data on various health metrics and lifestyle factors to identify potential links between obesity and diverticulitis. The findings could lead to new treatment strategies that leverage existing therapies for metabolic syndrome.

Who could benefit from this research

Good fit: Ideal candidates for this research are postmenopausal women who are experiencing obesity or related metabolic issues.

Not a fit: Patients who are not postmenopausal or do not have obesity-related conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved prevention and treatment strategies for diverticulitis, particularly in women affected by obesity.

How similar studies have performed: Previous research has indicated a link between obesity and various gastrointestinal conditions, suggesting that this approach may yield valuable insights.

Where this research is happening

Chapel Hill, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.