Investigating how noise-induced hearing loss affects Alzheimer's disease development and progression
The effect of noise induced hearing loss on Alzheimer's disease development and progression
This study is looking at how loud noises might affect hearing and possibly lead to Alzheimer's disease, and it's for anyone interested in understanding how their hearing health could relate to their memory and thinking skills.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project ID | NIH-10661373 on NIH RePORTER |
What this research studies
This research explores the relationship between noise exposure, hearing loss, and the development of Alzheimer's disease (AD). It aims to understand how environmental noise may contribute to cognitive decline and accelerate the onset of dementia. By examining the mechanisms behind noise-induced hearing loss and its potential role in AD progression, the study seeks to identify new risk factors and pathways that could inform prevention strategies. Patients may be involved in assessments of hearing and cognitive function to better understand these connections.
Who could benefit from this research
Good fit: Ideal candidates for participation include individuals with varying degrees of hearing loss or those who have been exposed to significant environmental noise.
Not a fit: Patients with no history of hearing loss or those not exposed to environmental noise may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing or delaying the onset of Alzheimer's disease in individuals exposed to high levels of noise.
How similar studies have performed: While the specific hypothesis regarding noise and Alzheimer's is novel, related research has shown that environmental factors can influence cognitive decline.
Where this research is happening
New Haven, United States
- Yale University — New Haven, United States (Active)
Researchers
- Principal investigator: Zhao, Hong-Bo — Yale University
- Study coordinator: Zhao, Hong-Bo
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.