Investigating how NIR therapy can help treat brain injuries in animal models.
Assessing the efficacy of NIR therapy to modulate shared secondary injury mechanisms in a murine model of ischemic stroke and porcine model of TBI
This study is looking at how near-infrared therapy might help heal brain injuries, like concussions, by testing it on young pigs to see how their brains respond, which could help us find better treatments for people with similar injuries.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-10973699 on NIH RePORTER |
What this research studies
This research focuses on understanding the effects of near-infrared (NIR) therapy on brain injuries, specifically traumatic brain injury (TBI), using animal models such as pigs. The study aims to assess behavioral and physiological changes in juvenile pigs after simulating a concussion, which can provide insights into age-specific responses to brain trauma. Advanced imaging techniques like MRI will be employed to evaluate the effectiveness of the therapy on brain structure and function. The findings could lead to improved treatment strategies for brain injuries in humans.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research would include individuals suffering from traumatic brain injuries, particularly children and young adults.
Not a fit: Patients with non-traumatic brain injuries or those who do not meet the age criteria may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic approaches for treating traumatic brain injuries in both children and adults.
How similar studies have performed: Previous research has shown promise in using animal models to study brain injuries and test new therapies, indicating that this approach could yield valuable insights.
Where this research is happening
Ann Arbor, United States
- University of Michigan at Ann Arbor — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Netzley, Alesa Hughson — University of Michigan at Ann Arbor
- Study coordinator: Netzley, Alesa Hughson
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.