Investigating how new hormone therapies affect blood sugar and fat levels in postmenopausal women veterans with prediabetes.
Official title: Effects of Novel Estrogens on Glucose and Lipids in Postmenopausal Prediabetic Women Veterans
Funded at Southeast Louisiana Veterans Health Care · NIH-10975938 · Data updated 2026-11-12
This study is looking at a new hormone therapy to see if it can help manage blood sugar and fat levels in overweight women veterans who have gone through menopause and are at risk for diabetes.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Southeast Louisiana Veterans Health Care NIH-funded |
| Lab location | 1 site (New Orleans, United States) |
| Project start | October 1, 2021 |
| Project end | September 30, 2026 |
| Funding year | 2025 |
| NIH project number | 5IK2CX002225-04 |
| Project ID | NIH-10975938 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are obese postmenopausal women veterans who have prediabetes or early diabetes.
✕Less likely to help
Patients who are not postmenopausal or do not have prediabetes may not benefit from this research.
What this research studies
This research focuses on the effects of a novel hormone therapy, combining conjugated estrogens and bazedoxifene, on glucose and lipid levels in obese postmenopausal women veterans who are at risk for diabetes. The study aims to determine whether this treatment can improve the function of insulin-producing cells and help regulate blood sugar levels without causing excess fat accumulation in the liver. By understanding these effects, the research seeks to provide new strategies for preventing metabolic issues related to menopause.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for managing blood sugar and reducing cardiovascular risks in postmenopausal women.
How similar studies have gone: Previous research has shown promise in using hormone therapies to manage metabolic dysfunction in similar populations, indicating potential for success in this approach.
Where this research is happening
-
Southeast Louisiana Veterans Health Care
New Orleans, United States Active
Researchers
- Principal investigator: Lovre, Dragana — Southeast Louisiana Veterans Health Care
- Study coordinator: Lovre, Dragana
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.