Investigating how new gut hormone treatments affect heart health

Causal Mechanisms of Novel Gut-Hormone Agonists on Cardiovascular Health

NIH-funded research Stanford University · NIH-10997143

This study is looking at how new medications that work with gut hormones can help improve heart health for people with diabetes and obesity, aiming to find out if they offer benefits beyond just helping with weight and blood sugar.

Quick facts

Grant typeFellowship grant
Study typeNIH-funded research
Funding institutionStanford University NIH-funded
Lab location1 site (Stanford, United States)
Project IDNIH-10997143 on NIH RePORTER

What this research studies

This research explores the effects of novel gut hormone agonists on cardiovascular health, particularly focusing on their impact on patients with diabetes and obesity. By examining how these treatments influence heart function and overall cardiovascular outcomes, the study aims to provide insights into their potential benefits beyond weight loss and blood sugar control. The research employs advanced techniques to analyze genetic and functional responses to these medications, which could lead to a better understanding of their cardiovascular benefits.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 21 and older who are living with diabetes and obesity.

Not a fit: Patients without diabetes or obesity may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatments for cardiovascular disease in patients with diabetes and obesity.

How similar studies have performed: Previous research has shown promising results with GLP-1 receptor agonists in improving cardiovascular outcomes, suggesting that this approach may yield significant insights.

Where this research is happening

Stanford, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.