Investigating how neuromodulation can improve bladder function after spinal cord injury
Official title: Effects of on-demand and early neuromodulation interventions on bladder function after spinal cord injury
Funded at University of Pittsburgh at Pittsburgh · NIH-11035476 · Data updated 2026-11-12
This study is looking at a new way to help people with spinal cord injuries regain better control over their bladder using a special technique that stimulates the nerves, and it's aimed at finding out if this could lead to better treatment options for those struggling with bladder issues.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project start | December 6, 2024 |
| Project end | November 30, 2026 |
| Funding year | 2025 |
| Award (this year) | $238,500 |
| NIH project number | 1R21NS140942-01 |
| Project ID | NIH-11035476 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with spinal cord injuries who experience bladder dysfunction.
✕Less likely to help
Patients without spinal cord injuries or those who do not experience bladder dysfunction may not benefit from this research.
What this research studies
This research focuses on improving bladder control in individuals with spinal cord injuries (SCI), a condition affecting over 350,000 people in the U.S. The study explores the use of epidural spinal cord stimulation (SCS) to activate nerves that control bladder function, which may help restore voluntary control. By testing this approach in animal models, the researchers aim to determine if SCS can evoke bladder reflexes and improve urinary function in those with chronic SCI. The findings could lead to new treatment options for managing bladder dysfunction in patients with SCI.
Why it matters
Potential benefit: If successful, this research could significantly enhance bladder control and quality of life for individuals with spinal cord injuries.
How similar studies have gone: Previous studies have shown promise in using spinal cord stimulation for bladder control, indicating potential for success in this innovative approach.
Where this research is happening
-
University of Pittsburgh at Pittsburgh
Pittsburgh, United States Active
Researchers
- Principal investigator: Gaunt, Robert a — University of Pittsburgh at Pittsburgh
- Study coordinator: Gaunt, Robert a
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.