Investigating how nerve connections change to help recovery after a stroke

Role of Axonal Sprouting Mediated Network Reorganization in Stroke Recovery

['FUNDING_CAREER'] · WASHINGTON UNIVERSITY · NIH-11056083

This study is looking at how the brain heals after a stroke, focusing on how brain cells can grow and reorganize to help people recover, and the findings could lead to better treatments for stroke patients.

Quick facts

Phase['FUNDING_CAREER']
Study typeNih_funding
SexAll
SponsorWASHINGTON UNIVERSITY (nih funded)
Locations1 site (SAINT LOUIS, UNITED STATES)
Trial IDNIH-11056083 on ClinicalTrials.gov

What this research studies

This research focuses on understanding the molecular and neuronal mechanisms that contribute to recovery following an ischemic stroke. The principal investigator, an MD/PhD neurologist, will explore how axonal sprouting and network reorganization in the brain can facilitate recovery. The project includes mentorship and training to ensure the investigator develops the skills necessary to lead future studies that could improve patient outcomes. Patients may benefit from insights gained into how the brain heals after injury.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 21 and older who have experienced an ischemic stroke.

Not a fit: Patients who have not suffered a stroke or those with chronic neurological conditions unrelated to stroke may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new strategies for enhancing recovery in stroke patients.

How similar studies have performed: Previous research has shown promise in understanding brain recovery mechanisms, suggesting that this approach could yield valuable insights.

Where this research is happening

SAINT LOUIS, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.