Investigating how nerve and immune systems interact to affect skin and gut inflammation
Official title: Neuro-immune regulation of inter-organ skin-gut inflammation
Funded at Weill Medical Coll of Cornell Univ · NIH-11097371 · Data updated 2026-11-12
This study is looking at how a special protein in the nervous system affects inflammation in the skin and gut, which could help find better treatments for people with conditions like inflammatory bowel disease (IBD) and skin issues.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | June 1, 2024 |
| Project end | May 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $128,250 |
| NIH project number | 5K99AI180354-02 |
| Project ID | NIH-11097371 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with inflammatory bowel diseases or chronic inflammatory skin conditions.
✕Less likely to help
Patients with isolated gastrointestinal issues that do not involve inflammatory skin conditions may not benefit from this research.
What this research studies
This research explores the complex interactions between the nervous and immune systems that influence inflammation in the skin and gut. It focuses on a specific neuropeptide called neuromedin U and its role in regulating immune responses related to inflammatory bowel diseases (IBD) and skin conditions. By understanding these interactions, the research aims to develop new therapeutic strategies for treating IBD and related inflammatory diseases. Patients with chronic skin and gut inflammation may find this research particularly relevant as it seeks to uncover underlying mechanisms that could lead to better treatment options.
Why it matters
Potential benefit: If successful, this research could lead to innovative therapies that improve treatment outcomes for patients suffering from inflammatory bowel diseases and related inflammatory conditions.
How similar studies have gone: Other research has shown promising results in targeting neuro-immune pathways for treating inflammatory diseases, suggesting that this approach may be effective.
Where this research is happening
-
Weill Medical Coll of Cornell Univ
New York, United States Active
Researchers
- Principal investigator: Yano, Hiroshi — Weill Medical Coll of Cornell Univ
- Study coordinator: Yano, Hiroshi
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.