Investigating how nerve and immune systems interact to affect skin and gut inflammation
Neuro-immune regulation of inter-organ skin-gut inflammation
['FUNDING_CAREER'] · WEILL MEDICAL COLL OF CORNELL UNIV · NIH-11097371
This study is looking at how a special protein in the nervous system affects inflammation in the skin and gut, which could help find better treatments for people with conditions like inflammatory bowel disease (IBD) and skin issues.
Quick facts
| Phase | ['FUNDING_CAREER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WEILL MEDICAL COLL OF CORNELL UNIV (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-11097371 on ClinicalTrials.gov |
What this research studies
This research explores the complex interactions between the nervous and immune systems that influence inflammation in the skin and gut. It focuses on a specific neuropeptide called neuromedin U and its role in regulating immune responses related to inflammatory bowel diseases (IBD) and skin conditions. By understanding these interactions, the research aims to develop new therapeutic strategies for treating IBD and related inflammatory diseases. Patients with chronic skin and gut inflammation may find this research particularly relevant as it seeks to uncover underlying mechanisms that could lead to better treatment options.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with inflammatory bowel diseases or chronic inflammatory skin conditions.
Not a fit: Patients with isolated gastrointestinal issues that do not involve inflammatory skin conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to innovative therapies that improve treatment outcomes for patients suffering from inflammatory bowel diseases and related inflammatory conditions.
How similar studies have performed: Other research has shown promising results in targeting neuro-immune pathways for treating inflammatory diseases, suggesting that this approach may be effective.
Where this research is happening
NEW YORK, UNITED STATES
- WEILL MEDICAL COLL OF CORNELL UNIV — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: YANO, HIROSHI — WEILL MEDICAL COLL OF CORNELL UNIV
- Study coordinator: YANO, HIROSHI
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.