Investigating how NEK2 affects the progression of multiple myeloma
Novel NEK2 signaling pathways in myeloma progression
This study is looking at how a gene called NEK2 affects multiple myeloma, a type of blood cancer, to help find better ways to treat patients by understanding how this gene helps cancer grow and resist treatments.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of Arkansas for Med Scis NIH-funded |
| Lab location | 1 site (Little Rock, United States) |
| Project ID | NIH-10843109 on NIH RePORTER |
What this research studies
This research focuses on understanding the role of the NEK2 gene in multiple myeloma, a type of blood cancer. By analyzing gene expression profiles from patients at different stages of treatment, the researchers aim to uncover how NEK2 contributes to cancer growth and resistance to therapies. They will explore the interactions between NEK2 and other proteins that may influence cancer cell survival and response to treatment. This work could lead to new strategies for targeting NEK2 to improve outcomes for patients with multiple myeloma.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with multiple myeloma, particularly those experiencing treatment resistance or relapse.
Not a fit: Patients with other types of cancers or those not diagnosed with multiple myeloma may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for multiple myeloma, potentially improving survival rates and quality of life for patients.
How similar studies have performed: Previous research has shown promising results in targeting similar pathways in other cancers, suggesting that this approach may be effective in multiple myeloma as well.
Where this research is happening
Little Rock, United States
- Univ of Arkansas for Med Scis — Little Rock, United States (Active)
Researchers
- Principal investigator: Zhan, Fenghuang — Univ of Arkansas for Med Scis
- Study coordinator: Zhan, Fenghuang
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.