Investigating how natriuretic peptides affect fat tissue and energy use
Natriuretic peptide and cGMP signaling in adipose tissue and energy metabolism
This study is looking at how certain hormones called natriuretic peptides affect fat cells in our bodies, which could help us find new ways to fight obesity and related health issues.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project ID | NIH-11047707 on NIH RePORTER |
What this research studies
This research explores the role of natriuretic peptides in regulating brown adipose tissue, which is important for energy metabolism and maintaining body temperature. By examining how these peptides influence fat cells, the study aims to understand their potential in combating obesity and related metabolic diseases. The approach includes both laboratory experiments and analysis of human adipose tissue to assess the effects of these hormones on fat cell behavior and energy expenditure.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 21 years old who are experiencing obesity or related metabolic conditions.
Not a fit: Patients who are not overweight or do not have metabolic disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for obesity and type II diabetes by enhancing the body's ability to burn fat.
How similar studies have performed: Previous studies have shown promising results in using similar approaches to activate brown fat and improve metabolic health.
Where this research is happening
Nashville, United States
- Vanderbilt University Medical Center — Nashville, United States (Active)
Researchers
- Principal investigator: Collins, Sheila — Vanderbilt University Medical Center
- Study coordinator: Collins, Sheila
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.