NIH-funded research R15 grant

Investigating how Myopalladin affects heart muscle function and disease.

Official title: Myopalladin’s Role in Cardiac Muscle Function and Disease

Funded at Wichita State University · NIH-10606271 · Data updated 2026-11-12

This study is looking at a protein called Myopalladin that helps heart muscle cells work properly, and by understanding how it interacts with other parts of the cell, we hope to find new ways to treat heart diseases that affect many people.

Quick facts

Grant typeR15 grant
Study typeNIH-funded research
Funding institutionWichita State University
NIH-funded
Lab location1 site (Wichita, United States)
Project startSeptember 1, 2021
Project endAugust 31, 2025
Funding year2022
Award (this year)$285,862
NIH project number3R15GM140422-01A1S2
Project IDNIH-10606271 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals with known cardiac abnormalities or a family history of cardiac diseases.

Less likely to help

Patients with non-cardiac related health issues or those without any cardiac abnormalities may not receive benefit from this research.

What this research studies

This research focuses on understanding the role of Myopalladin, a protein that is crucial for the function of cardiac muscle cells. By examining how Myopalladin interacts with actin filaments and other cellular components, the research aims to uncover mechanisms that contribute to various cardiac diseases, including cardiomyopathies. The approach involves biochemical assays and bioinformatics to analyze the cellular architecture and function in heart tissues. Patients may benefit from insights gained that could lead to new treatments for heart conditions.

Why it matters

Potential benefit: If successful, this research could lead to improved treatments for heart diseases by targeting the underlying mechanisms of cardiac muscle dysfunction.

How similar studies have gone: Other research has shown promising results in understanding cardiac muscle function through similar biochemical approaches, indicating potential for success in this area.

Where this research is happening

  • Wichita State University
    Wichita, United States
    Active

Researchers

  • Principal investigator: Beck, Moriah R — Wichita State University
  • Study coordinator: Beck, Moriah R

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.