Investigating how multiple health conditions and stress affect dementia risk and cognitive decline in older adults

Multimorbidity Trajectories, Psychosocial Resilience and Stress, and Risk of Dementia and Poor Cognitive Functioning

NIH-funded research Univ of Maryland, College Park · NIH-10684061

This study looks at how having several long-term health issues might affect the chances of older adults developing dementia or having memory problems, while also considering how stress and resilience play a role, with the goal of finding ways to better support these individuals.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniv of Maryland, College Park NIH-funded
Lab location1 site (College Park, United States)
Project IDNIH-10684061 on NIH RePORTER

What this research studies

This research examines the relationship between having multiple chronic health conditions (multimorbidity) and the risk of developing dementia or experiencing cognitive decline in older adults. It also explores how factors like psychosocial resilience and stress may influence this relationship. By analyzing data from the Health Retirement Study, the research aims to identify patterns and differences in dementia risk based on gender and race. The findings could help in understanding how to better support older adults facing these challenges.

Who could benefit from this research

Good fit: Ideal candidates for this research are older adults who have multiple chronic health conditions and are at risk for dementia.

Not a fit: Patients who are younger or do not have any chronic health conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for preventing dementia and enhancing cognitive health in older adults.

How similar studies have performed: Previous research has shown promising results in understanding the links between chronic conditions, psychosocial factors, and cognitive health, making this approach both relevant and potentially impactful.

Where this research is happening

College Park, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementia
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.