Investigating how mucus functions in the lungs during health and disease
Multi-Scale Investigations of Respiratory Mucus/Mucin Structure and Function in Health and Disease
This study is looking at how mucus works in our lungs to help keep us healthy, especially for people with asthma or COPD, to find new ways to improve lung health.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project ID | NIH-10892090 on NIH RePORTER |
What this research studies
This research focuses on understanding the mucus clearance system, which is crucial for defending the airways against infections and toxins. The team will explore the structure and function of mucins, the main components of mucus, to identify how they behave in healthy lungs compared to those with chronic diseases like asthma and COPD. By examining the organization of mucins and their interactions with other substances, the research aims to uncover important insights that could lead to new therapies for respiratory conditions. Patients may be involved in studies that assess mucus properties and their implications for lung health.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with chronic respiratory conditions such as asthma, COPD, or cystic fibrosis.
Not a fit: Patients without chronic respiratory diseases or those with acute respiratory infections may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for chronic respiratory diseases by enhancing our understanding of mucus function.
How similar studies have performed: Previous research has shown promise in understanding mucus function, but this investigation aims to fill significant gaps in knowledge, making it a novel approach.
Where this research is happening
Chapel Hill, United States
- Univ of North Carolina Chapel Hill — Chapel Hill, United States (Active)
Researchers
- Principal investigator: Boucher, Richard Charles — Univ of North Carolina Chapel Hill
- Study coordinator: Boucher, Richard Charles
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.