Investigating how MSC exosomes affect immune cell function in ME/CFS
Official title: MSC exosomes as probes for ME/CSF immune cell dysfunction
Funded at Nova Southeastern University · NIH-11033351 · Data updated 2026-11-12
This study is looking at how tiny particles from bone marrow cells might help us understand the immune and energy problems in people with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), and patients can help by sharing blood samples to support this important research.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Nova Southeastern University NIH-funded |
| Lab location | 1 site (Fort Lauderdale-Davie, UNITED STATES) |
| Project start | December 1, 2024 |
| Project end | November 30, 2026 |
| Funding year | 2025 |
| Award (this year) | $224,070 |
| NIH project number | 1R21AI187895-01 |
| Project ID | NIH-11033351 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.
✕Less likely to help
Patients with conditions unrelated to ME/CFS or those who do not have a diagnosis of ME/CFS may not benefit from this research.
What this research studies
This research focuses on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), a debilitating condition characterized by severe fatigue and other symptoms. The study aims to explore the role of exosomes derived from bone marrow mesenchymal stromal cells in understanding immune and metabolic dysfunctions associated with ME/CFS. By analyzing how these exosomes influence immune cell behavior, the research seeks to uncover potential therapeutic pathways. Patients may be involved in providing blood samples to help identify the underlying mechanisms of their condition.
Why it matters
Potential benefit: If successful, this research could lead to new targeted therapies for ME/CFS, improving the quality of life for patients.
How similar studies have gone: Previous research has shown promise in using exosomes for therapeutic purposes in various conditions, suggesting potential success for this novel approach.
Where this research is happening
-
Nova Southeastern University
Fort Lauderdale-Davie, United States Active
Researchers
- Principal investigator: Beljanski, Vladimir — Nova Southeastern University
- Study coordinator: Beljanski, Vladimir
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.