Investigating how modified proteins can regulate biological processes
Biological Regulation Studied In Vitro and In Cellulo with Modified Proteins
['FUNDING_OTHER'] · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · NIH-11082356
This study is looking at new ways to change the building blocks of proteins to help us understand important processes in our cells, which could lead to better treatments for patients.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ARIZONA STATE UNIVERSITY-TEMPE CAMPUS (nih funded) |
| Locations | 1 site (TEMPE, UNITED STATES) |
| Trial ID | NIH-11082356 on ClinicalTrials.gov |
What this research studies
This research focuses on developing techniques to modify ribosomal RNA structures, allowing for the incorporation of unique amino acids into proteins. By using these modified ribosomes, the study aims to explore key biochemical processes such as protein glycosylation and phosphorylation, which are crucial for regulating cellular functions. Patients may benefit from insights gained about how these modifications affect gene expression and protein interactions, potentially leading to new therapeutic strategies. The research involves both in vitro and in vivo approaches to ensure comprehensive understanding.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions related to protein regulation and modification, such as certain genetic disorders or cancers.
Not a fit: Patients with conditions unrelated to protein modification or those who do not have a genetic basis for their disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that better regulate biological processes in various diseases.
How similar studies have performed: Previous research has shown promise in using modified proteins for therapeutic purposes, indicating that this approach could yield significant advancements.
Where this research is happening
TEMPE, UNITED STATES
- ARIZONA STATE UNIVERSITY-TEMPE CAMPUS — TEMPE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HECHT, SIDNEY M. — ARIZONA STATE UNIVERSITY-TEMPE CAMPUS
- Study coordinator: HECHT, SIDNEY M.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.